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Ingredient file // Animal protein

Spray-dried Beef Plasma

Concentrated beef protein with limited health evidence

Spray-dried beef plasma is the liquid part of cattle blood, separated from the cells and dried into powder. It supplies concentrated protein and helps bind food. Dog studies of digestion, immunity and joint health mostly tested porcine or unspecified animal plasma.

What it is
The liquid portion of cattle blood, separated from blood cells and dried into a protein powder.
Made from
Blood collected during cattle slaughter
Main job
Protein and binding
Typical amount
Not published for beef plasma
Watch for
A diagnosed beef allergy
Not the same as
Beef blood meal

Straight answer

Is Spray-dried Beef Plasma safe for dogs?

Read it as protein, then check the food

When beef plasma sits low on a label, expect a small protein and texture contribution. Check the named proteins around it and whether the package is a complete food or a topper. Avoid it for a dog with diagnosed beef allergy. Do not buy it for an immune or joint promise.

Why it is in the food
Protein and binding

Our read // In our catalog

In 1 of every 1,602 foods we track

Share of foods that list it

<1%

2 of the 3,204 foods with an ingredient list on file, from 1 brand. All dog food topper.

Each square is 1% of the catalog

Where it sits on the label

Median position 4. In the top five of 2 foods, so it is usually a main ingredient.

Top five List position, heaviest first

Who leans on it

100%

of the foods that list it are from Nulo. 1 brand use it in total.

What it is

How it is made

Beef processing produces blood alongside meat. Collectors separate the plasma from blood cells, then dry it quickly. This turns a perishable slaughterhouse stream into a powder that food makers use for protein and binding.9

  1. 01 // Source Collected cattle blood Blood is collected during cattle slaughter and given an anticoagulant so it stays liquid.
  2. 02 // Process Cells separated A centrifuge spins out blood cells, leaving liquid plasma rich in soluble proteins.
  3. 03 // Process Plasma spray dried Fine droplets of plasma meet heated air and rapidly lose water while many proteins remain soluble.
  4. 04 // Output Beef plasma powder The dry powder arrives at food plants ready to add protein or bind water and fat.

What is in it

Composition, dry matter

87

% protein

Crude protein in one tested commercial beef plasma lot. It is a concentrated protein ingredient, although one lot is not a supplier guarantee.

Crude protein 86.7%5
Ash 8.1%5
Fat 0.5%5

These rows describe one commercial lot, not a fixed specification. Another bovine lot had less protein and more fat after accounting for its published moisture, so supplier analyzes matter.5,6

Why it is in the bag

What the manufacturer gets

  1. 01

    Adds animal protein

    Removing water leaves a powder dominated by protein. It raises the recipe's protein content without adding much fat.5

  2. 02

    Binds water and fat

    Plasma proteins gel when heated and help hold wet food together. That binding role matters most in canned pieces and other moist foods.9

  3. 03

    Uses a slaughterhouse stream

    Separating and drying plasma gives collected blood a food use. Those processing steps add cost, which can limit how much manufacturers include.9

How much Dog studies tested 1 to 12% porcine or unspecified animal plasma; a typical beef-plasma amount has not been published.1,2,4

Our read // The claims

What the evidence supports

Strong: controlled studies in dogs agree. Some: small or mixed dog data. Thin: mechanism or lab work only. None: nothing, or the evidence points the other way.

  1. Brands say

    It supplies concentrated beef protein

    Evidence

    1. Strong
    2. Some
    3. Thin
    4. None

    A tested commercial beef plasma lot measured 86.7% crude protein and 0.5% fat on a dry matter basis. That supports its role as a protein ingredient, but does not reveal how much the finished food contains.5

  2. Brands say

    It improves digestion and reduces stool

    Outruns the evidence

    Evidence

    1. Strong
    2. Some
    3. Thin
    4. None

    Across short trials involving 22 dogs, animal plasma improved dry matter digestion and reduced dry fecal output by about 15%. A 2019 eight-dog porcine-plasma trial found no fecal-output difference. Beef plasma in a topper remains untested.1,2

  3. Brands say

    Beef plasma eases arthritic joints

    Outruns the evidence

    Evidence

    1. Strong
    2. Some
    3. Thin
    4. None

    A 42-day trial in 24 arthritic dogs found lower lameness scores with 4% animal plasma. Its source species was unstated, diets differed in fish oil, and supplier employees coauthored the paper. Beef-plasma toppers remain untested.4

  4. Brands say

    Its antibodies boost a dog's immunity

    Outruns the evidence

    Evidence

    1. Strong
    2. Some
    3. Thin
    4. None

    A single 12-dog trial found higher fecal IgA with 8% porcine plasma, 4.8 mg/g DM versus 3.4 mg/g DM on the control diet, P<0.05. IgA is one immune marker, not proof plasma antibodies survived digestion or that dogs resisted illness. A plasma supplier funded the trial.3

  5. Brands say

    It makes dog food taste better

    Outruns the evidence

    Evidence

    1. Strong
    2. Some
    3. Thin
    4. None

    In a preference test with 20 dogs, the food without 4% porcine plasma was chosen first more often. Acceptance in other feeding trials does not show a taste advantage for beef plasma.2,3

Straight answers

What owners ask

  1. Q01

    Is it just filler?

    No

    It supplies concentrated animal protein, and plasma proteins bind water and fat in food. Those are real jobs. Its presence on a label does not tell you how much protein it contributes to the whole recipe.5,9

  2. Q02

    Is it beef blood meal?

    No

    Plasma is separated from blood cells before drying. Blood meal contains a different mix of blood components, and a direct analysis found different protein and mineral figures. Read them as separate ingredients.5,9

  3. Q03

    Can a beef-allergic dog eat it?

    Avoid it

    Beef plasma contains bovine proteins. Researchers identified one plasma protein as an allergen in a dog with a beef reaction. Keep this ingredient out of a diet for a dog with diagnosed beef allergy.7,8

Who uses it

Brands, best sellers and the company it keeps

Top brands, by foods that list it

  1. Nulo 2 / 117

Foods that list it / all the brand's recipes we track.

Usually listed with, share of the foods that list it

  1. Salmon Oil 100%
  2. Mixed Tocopherols 100%
  3. Salmon 50%
  4. Dried Egg 50%
  5. Zinc Sulfate 50%
  6. Xanthan Gum 50%
  7. Beef 50%
  8. Beef Heart 50%
  9. Beef Liver 50%
  10. Glucosamine Hydrochloride 50%
  11. Chondroitin Sulfate 50%

On the shelf

Foods that list Spray-dried Beef Plasma

2 foods in our catalog list it, highest on the label first.

Sources

What we read

Checked October 1, 2026.

  1. 1 Effects of spray-dried animal plasma on intake and apparent digestibility in dogs Journal of Animal Science, 2004 // Journal
  2. 2 Spray-dried porcine plasma in dog foods: implications on digestibility, palatability and haematology Semina: Ciências Agrárias, 2019 // Journal
  3. 3 Effects of spray-dried plasma on nutrient digestibility, fecal metabolites, microbiota, and immune and inflammatory biomarkers in adult dogs Journal of Animal Science, 2025 // Journal
  4. 4 Effects of spray-dried animal plasma on inflammatory indicators, antioxidant capacity, and joint health in senior dogs Journal of Animal Science, 2026 // Journal
  5. 5 Impact of storage conditions on protein oxidation of rendered by-product meals Translational Animal Science, 2020 // Journal
  6. 6 Growth performance of weanling pigs fed diets containing spray-dried bovine plasma or hydrolyzed spray-dried bovine plasma Animal Feed Science and Technology, 2022 // Journal
  7. 7 Critically appraised topic on adverse food reactions of companion animals (2): common food allergen sources in dogs and cats BMC Veterinary Research, 2016 // Journal
  8. 8 Identification of Bovine Serum Albumin as an IgE-Reactive Beef Component in a Dog with Food Hypersensitivity against Beef Journal of Veterinary Medical Science, 2007 // Journal
  9. 9 Spray-Dried Animal Plasma as a Multifaceted Ingredient in Pet Food Animals, 2023 // Journal
An ingredient on its own tells you very little. What matters is how much of it there is and where it sits in the list. That is why we weigh the top five rather than reacting to any single name further down. Back to the wiki

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