Ingredient file // Vitamin or mineral
Thiamine Mononitrate
A tiny B1 addition with a real job
Thiamine mononitrate is a manufactured form of vitamin B1 added in small amounts to dog food. It helps the finished food meet a dog's B1 needs, which matter for using food for energy and keeping the nervous system working normally.
Role in the food Supporting nutrient- What it is
- A crystalline form of vitamin B1 used to raise the thiamine content of food.
- Made from
- Thiamine hydrochloride and nitric acid
- Main job
- Adds vitamin B1
- Typical amount
- Not published
- Watch for
- Processing can lower finished B1
- Not the same as
- Thiamine hydrochloride
Straight answer
Is Thiamine Mononitrate safe for dogs?
Read it as fortification, then check the diet
Expect thiamine mononitrate near the end of the ingredient list with the other vitamins. Check that the bag says the food is complete and balanced for your dog's life stage. The ingredient name tells you B1 was added; it does not tell you how much survived processing.
- Why it is in the food
- Adds vitamin B1
- Watch for
- Too little finished B1
Our read // In our catalog
In 1 of every 1 foods we track
Share of foods that list it
83%
2,671 of the 3,204 foods with an ingredient list on file, from 89 brands. 1,706 dry dog food, 825 wet dog food, 51 dog food topper.
Each square is 1% of the catalog
Where it sits on the label
Median position 22. In the top five of 6 foods, so it is usually a minor ingredient.
Above the salt
Usually listed after the salt, which caps it at roughly 1% of the recipe in 91% of foods.
Price per lb
Median of the cheapest bag price across 1,480 priced foods, about level with the catalog. The price is the food's, not the ingredient's.
Who leans on it
7%
of the foods that list it are from Purina. 89 brands use it in total.
The story
How vitamin B1 went from rice mystery to recalls
Thiamine's story starts with chickens. After returning to Java in 1887 as a Dutch medical officer, Christiaan Eijkman saw that birds fed polished rice bought for the army developed polyneuritis resembling beriberi. When their feed switched to regular rice with its silver outer layer, they recovered. Eijkman concluded that feed carried an agent that could prevent or cure the disease. He won the 1929 Nobel Prize, and in 1936 Robert Williams first synthesized thiamine, making factory-made B1 possible.10
Thiamine mononitrate is the dry, crystalline salt of that synthetic vitamin. In a rule published December 9, 1983, FDA affirmed it as generally recognized as safe for human food, used as a nutrient supplement at levels set by good manufacturing practice. Dog food uses it for the same job: topping up a vitamin that cooking heat wears down.2,4
The newest turning point came in 2026. On February 17, Go Raw LLC began a recall over low thiamine. In a March 13 advisory, FDA said 8 lots of Quest Cat Food it tested held anywhere from no detectable thiamine to 0.85 mg per kg, far under the 5.6 mg cat minimum. On June 8 the recall grew to a Steve's Real Food chicken recipe sold for cats and dogs. The company said B1 test results vary even in foods formulated with extra.11,12
What it is
How it is made
Vitamin makers synthesize thiamine and convert it into mononitrate crystals. Dog food makers add the concentrated powder through a vitamin premix so a small, measured amount of B1 enters the recipe.2,3,4
- 01 // Source Thiamine hydrochloride Manufacturers start with another manufactured form of vitamin B1, thiamine hydrochloride.
- 02 // Process Dissolved The hydrochloride form is dissolved in an alkaline solution before its salt form is changed.
- 03 // Process Nitrate added Nitric acid makes thiamine mononitrate separate from the solution as crystals.
- 04 // Output B1 crystals The crystalline powder is blended into a vitamin premix for food production.
What is in it
Composition, dry matter
81
% active B1
Pure mononitrate supplies about 0.81 gram of thiamine per gram. That conversion matters when a manufacturer calculates how much B1 to add.
Why it is in the bag
A small dose of vitamin B1, not filler
- Main nutrition
- Supporting nutrient
- Does a job
- Mostly filler
Dogs cannot make thiamine, so their food has to supply it. Makers add this manufactured form of B1 and may add extra before cooking, because processing can destroy much of the thiamine in a recipe. It sits near the end of the list because ingredients go by weight and the B1 target is tiny.2,4,5,7
-
01
Meets the B1 target
Dogs must get thiamine from food. A measured addition helps a recipe meet the finished food requirement for normal metabolism and nervous system function.2,5
-
02
Allows for cooking losses
Heat can lower thiamine in a recipe. Manufacturers may add extra before cooking, then account for what remains in the finished food.2,5
-
03
Fortifies at scale
The finished food target is measured in milligrams per kilogram. A vitamin premix lets a plant distribute that small amount through a much larger batch.2,3,5
How much AAFCO specifies at least 2.25 mg of thiamine per kg of finished dog food on a dry matter basis; the mononitrate addition varies by recipe.5
Our read // The claims
What the evidence supports
Strong: controlled studies in dogs agree. Some: small or mixed dog data. Thin: mechanism or lab work only. None: nothing, or the evidence points the other way.
-
Brands say
Added B1 supports normal metabolism and nerves
Evidence
- Strong
- Some
- Thin
- None
In a 5-dog case series, B1-deficient meat was linked to neurologic disease, and 2 adult dogs improved with thiamine treatment. Adequate B1 matters; the cases did not test mononitrate against another B1 source.1,2
-
Brands say
Added B1 covers losses from cooking
Evidence
- Strong
- Some
- Thin
- None
AAFCO warns that processing may destroy up to 90% of a diet's thiamine. A veterinary review describes adding synthetic thiamine before cooking, but losses vary by recipe and process. The ingredient listing cannot prove the finished amount.2,5
-
Brands say
This B1 form stays stable in kibble
Outruns the evidence
Evidence
- Strong
- Some
- Thin
- None
Supplier tests reported 97 to 107% mononitrate recovery in pelleted feed after 3 months at room temperature. That supports stability in the tested pellets, but pellets are not extruded kibble and the result is not a shelf life guarantee.3
-
Owners say
Extra B1 gives healthy dogs more energy
Outruns the evidence
Evidence
- Strong
- Some
- Thin
- None
The 5-dog case series concerned deficiency and treatment, not an energy boost in adequately fed dogs. B1 is needed to use food for energy, but extra B1 has not been shown to improve a healthy dog's stamina.1,2
-
Owners say
The nitrate makes this ingredient dangerous
Outruns the evidence
Evidence
- Strong
- Some
- Thin
- None
Nitrate is part of this vitamin salt's chemical form. In a 2025 feed additive review, EFSA judged thiamine mononitrate safe for target animals. Its name alone is not evidence of a harmful nitrate dose.3,4
The research
Studies worth knowing
Published research we read for this page, dog studies first.
-
1981 // Controlled feeding trial
B1-starved beagle puppies stopped eating, then developed nerve disease8
23 beagle puppies, 2 to 5 months old
Found. Puppies fed a ration with almost no thiamine ate less and stopped growing for about 58 days on average. Then 8 of 11 developed a neurologic syndrome with seizures and weakness, and 3 others had a sudden death syndrome.
What it means. Lost appetite and stalled growth came weeks before nerve signs, so an early B1 shortfall could be mistaken for poor appetite.
-
1986 // Feeding trial, brain exam
Long B1 shortage damaged gray matter in puppy brains9
22 beagle puppies, 2 to 5 months old
Found. After a mean of 84 days (range 32 to 134) on a thiamine-deficient ration, 8 of 11 deficient puppies had brain lesions, mostly in gray matter. The damage progressed from spongy tissue changes to tissue death. Controls received weekly thiamine injections.
What it means. Prolonged B1 shortage injures the brain itself, not just appetite, so steady daily intake from a complete food matters.
Straight answers
What owners ask
-
Q01
Is it just filler?
NoIt supplies vitamin B1, which dogs must get from food. Its amount is small because the dietary target is small. It has a specific nutritional job.2,5
-
Q02
Why is it near the end?
Tiny doseIngredients are listed by weight, and B1 is needed in milligram amounts per kilogram of food. A place near the other added vitamins is expected.5,7
-
Q03
Does nitrate mean preservative?
NoHere, nitrate names part of the thiamine salt. The ingredient is added to supply vitamin B1, not to preserve the food.3,4
Who uses it
Brands, best sellers and the company it keeps
Top brands, by foods that list it
Foods that list it / all the brand's recipes we track.
Plus 79 more brands.
Amazon best sellers that list it
- #1 Blue Life Protection Formula Adult Chicken and Brown Rice Recipe Dry Dog Food
- #2 Purina One SmartBlend Adult Dog Lamb & Rice Formula Dry Dog Food
- #3 Purina Pro Plan Adult Complete Essentials Shredded Blend Chicken & Rice Formula Dry Dog Food
- #4 Hill’s Science Diet Light Small & Mini Chicken Recipe Dry Dog Food
- #5 Blue Life Protection Formula Adult Small Breed Chicken and Brown Rice Recipe Dry Dog Food
- #6 Hill’s Science Diet Adult Sensitive Stomach & Skin Chicken Recipe Dry Dog Food
- #7 Stella & Chewy’s Marie’s Magical Dinner Dust Cage-Free Chicken Recipe Freeze-Dried Raw Dog Food Topper
- #8 Diamond Naturals Skin & Coat Formula All Life Stages Salmon & Potato Formula Dry Dog Food
Rank on Amazon's dog food best seller list, checked October 2026.
Usually listed with, share of the foods that list it
- Chicken 43%
- Mixed Tocopherols 38%
- Chicken Fat 34%
- Natural Flavor 34%
- Peas 30%
- Flaxseed 27%
- Chicken Meal 26%
- Brown Rice 23%
- Carrots 19%
- Sweet Potatoes 16%
- Beef 16%
- Dried Plain Beet Pulp 15%
On the shelf
Foods that list Thiamine Mononitrate
2,671 foods in our catalog list it. These 60 list it highest on the label.
Grandma Lucy'sGrandma Lucy’s Organic Banana & Sweet Potato Dog Food Topper
Grandma Lucy'sGrandma Lucy’s Organic Apple Dog Food Topper
PurinaPurina Beyond Mixers+ Immune Support Chicken Bone Broth Dog Food Topper
Evanger'sEvanger’s Super Premium Heritage Classic Chicken & Rice Dog Food Topper
Dave's Pet FoodDave’s Pet Food Restricted Diet Sodium Wet Dog Food
Evanger'sEvanger’s Grain Free Braised Beef Chunks with Gravy - packed by hand! Wet Dog Food
TruDogTruDog Elevate Smoky BBQ Stew Grain Free Shredded Chicken Stew w/ Sweet Potat Wet Dog Food
BIXBIBixbi Rawbble Grain-Free Freeze-Dried Dog Food
Against the GrainAgainst the Grain The Good Egg - Steak ‘n Egg Wet Dog Food
Against the GrainAgainst the Grain The Good Egg - Bacon N Eggs Scramble Wet Dog Food
HaloHalo Elevate Smoky BBQ Stew Grain Free Shredded Chicken Stew w/ Sweet Potat Wet Dog Food
ZignatureZignature Inception Chicken Recipe Food Can Wet Dog Food Show 48 more
Grandma Lucy'sGrandma Lucy’s Organic Pumpkin Dog Food Topper
Grandma Lucy'sGrandma Lucy’s Organic Blueberry Dog Food Topper
Evanger'sEvanger’s Heritage Classic Lamb & Rice Dinner Wet Dog Food
Evanger'sEvanger’s Roasted Chicken Drummet Dinner - packed by hand! Grain-Free Wet Dog Food
Evanger'sEvanger’s EVX Restricted Diet: Weight Management Wet Dog Food
Evanger'sEvanger’s Heritage Classic Senior & Weight Management Wet Dog Food
Evanger'sEvanger’s Super Premium EVX Restricted Diet: Skin & Coat Wet Dog Food
CesarCesar Home Delights Hearty Chicken & Noodle Dinner in Sauce Wet Dog Food
Evanger'sEvanger’s Chunky Chicken Casserole - packed by hand! Wet Dog Food
Evanger'sEvanger’s EVX Restricted Diet: Digestion Bland Diet Wet Dog Food
Evanger'sEvanger’s Grain Free; Super Premium Chicken Dinner Wet Dog Food
ZignatureZignature Inception Pork Recipe Food Can Wet Dog Food
Natural BalanceNatural Balance Platefulls Tender Carrot, Potato & Beef Recipe Wet Dog Food
PurinaPurina Pro Plan Sport Adult High Protein Beef & Bison Entrée Classic Wet Dog Food
ZignatureZignature Inception Pork Formula Dry Dog Food
WysongWysong Archetype Burgers Freeze-Dried Raw Dog Food
WellnessWellness Core 95% Turkey & Spinach Grain-Free Wet Dog Food
WellnessWellness Core 95% Chicken & Broccoli Grain-Free Wet Dog Food
Evanger'sEvanger’s Grain Free LID Venison + Beef Dinner Wet Dog Food
Evanger'sEvanger’s Grain Free Duck & Sweet Potato Dinner Wet Dog Food
ZignatureZignature Essence LIR Landfowl Recipe Food Can Grain-Free Wet Dog Food
ZignatureZignature Inception Fish Recipe Food Can Wet Dog Food
Natural BalanceNatural Balance Platefulls Savory Duck & Pumpkin Recipe Wet Dog Food
The Honest KitchenThe Honest Kitchen Tender Turkey One Pot Stew Wet Dog Food
The Honest KitchenThe Honest Kitchen Slow Cooked Chicken One Pot Stew Wet Dog Food
InstinctInstinct Raw Boost RawBoost+ Mixers Tranquility Recipe Dog Food Topper
PurinaPurina Pro Plan Adult 7+ Senior Complete Essentials Chicken & Rice Entrée Classic Wet Dog Food
ZignatureZignature Select Cuts Turkey Formula with Super Grains Dry Dog Food
ZignatureZignature Inception Fish Formula Dry Dog Food
WysongWysong Fundamentals Dry Dog Food
GatherGather Free Acres Organic Free-Run Chicken Recipe for Adult Dogs Grain-Free Dry Dog Food
PurinaPurina Beneful Chicken & Carrots Loaf Wet Dog Food
Dave's Pet FoodDave’s Pet Food Bland Diet Pouches Dave’s Bland Duck & Pumpkin Pouch Recipe for Dogs / 10 Pack - Pou Wet Dog Food
Gravy TrainGravy Train Ground Dinner With Chicken Wet Dog Food
Evanger'sEvanger’s Organic Turkey with Potato & Carrots Dinner for Dogs Grain-Free Wet Dog Food
Evanger'sEvanger’s EVX Restricted Diet: Hip & Joint and Senior Support Grain-Free Wet Dog Food
ZignatureZignature Essence LIR Ranch Recipe Food Can Grain-Free Wet Dog Food
ZignatureZignature Original Food Lamb Formula Grain-Free Wet Dog Food
ZignatureZignature Original Food Turkey Formula Grain-Free Wet Dog Food
The Honest KitchenThe Honest Kitchen Roasted Beef One Pot Stew Wet Dog Food
Open FarmOpen Farm Icelandic Cod & Herring Grain-Free Wet Dog Food
PedigreePedigree Chopped Ground Dinner Adult Pouch, Chicken Wet Dog Food
PedigreePedigree High Protein Chopped Ground Dinner Can, Chicken & Duck Wet Dog Food
InstinctInstinct Freshly Crafted Meals Cage-Free Chicken Recipe Wet Dog Food
PurinaPurina Beneful Freshly Prepared Stews Turkey Dinner with Spinach and Ditalini Pasta in Gravy Wet Dog Food
PurinaPurina Beneful Freshly Prepared Stews Chicken Dinner with Carrots and Rice in Gravy Wet Dog Food
BlueBlue Wilderness Wild Meals Chicken & Sweet Potato Wet Dog Food
FirstMateFirstMate Pacific Ocean Fish Weight Control Formula Grain-Free Dry Dog Food Sources
What we read
Checked September 1, 2026.
- 1 Thiamine deficiency in dogs due to the feeding of sulphite preserved meat
- 2 The Role of Thiamine and Effects of Deficiency in Dogs and Cats
- 3 Assessment of the feed additives thiamine hydrochloride (3a820) and thiamine mononitrate (3a821) (vitamin B1) for all animal species for the renewal of their authorisation (Kaesler Nutrition GmbH)
- 4 21 CFR § 184.1878 - Thiamine mononitrate
- 5 AAFCO DOG FOOD NUTRIENT PROFILES
- 6 Nutritional Guidelines for Complete and Complementary Pet Food for Cats and Dogs
- 7 Reading Labels
- 8 Experimentally induced thiamine deficiency in beagle dogs: clinical observations
- 9 Experimentally induced thiamine deficiency in beagle dogs: pathologic changes of the central nervous system
- 10 Christiaan Eijkman (1856 - 1930)
- 11 FDA Advisory: Certain Lots of Quest Cat Food Pose Serious Health Risks Due to Extremely Low Levels of Thiamine
- 12 GO Raw LLC. Expands Voluntary Recall to Include One Lot of Steve's Real Food Freeze-Dried Chicken Recipe Due to Low Thiamine (Vitamin B1) Levels